Supporting people with Cri du Chat Syndrome and their families

Genetics

Cri du Chat Syndrome is caused by the deletion of some genetic material (DNA). The deletion is on the short arm of Chromosome 5. This is known as 5p- in medical terms.

The diagrams in the medical section below show the layout of Chromosome 5, and in combination with a genetic diagnosis can show which parts of the chromosome are missing.

These diagrams contain medical terms that some people may find unpleasant. You should also not take them as a guide to how your child will develop. Much about this syndrome is unknown, and every child is different.

Chromosome diagrams

These diagrams show which syndrome features have been found to correspond to particular deletions across a number of different studies. As you can see, some are contradictory or vague, so these should not be used as a prediction tool for how a child will develop.

Chromosome 5 (short arm)

Source unknown. Please let us know if you know where this diagram was first published.

Chromosome 5 (short arm)

Source unknown. Please let us know if you know where this diagram was first published.